A comprehensive assessment of cognitive function in the common genetic generalized epilepsy syndromes

Abstract

Background and purpose: Considered to be benign conditions, the common genetic generalized epilepsy (GGE) syndromes are now known to be frequently accompanied by cognitive dysfunction. However, unresolved issues impede clinical management of this common comorbidity, including which cognitive abilities are most affected, whether there are differences between syndromes and how seizure type and mood symptoms affect cognitive dysfunction. We provide a detailed description of cognitive ability and evaluate factors contributing to cognitive dysfunction. Methods: A total of 76 adults with GGE were assessed with the Woodcock Johnson III Tests of Cognitive Abilities. Results: Scores on tests of overa..